Tagata TEL-AML1 Fusion Gene Mutation
Igoa o oloa
HWTS-TM016 Tagata TEL-AML1 Fusion Gene Mutation Detection Kit (Fluorescence PCR)
Epidemiology
Acute lymphoblastic leukemia (ALL) ole ma'i sili ona taatele ile tamaitiiti.I tausaga talu ai nei, ua suia ai le ma'i leukemia (AL) mai le ituaiga MIC (morphology, immunology, cytogenetics) i le MICM type (fa'aopoopoina o su'ega mole mole biology).I le 1994, na iloa ai o le fusuaga o le TEL i le tamaitiiti na mafua mai i le fa'aliliuina ole chromosomal t(12;21)(p13;q22) ile B-lineage acute lymphoblastic leukemia (ALL).Talu mai le mauaina o le AML1 fusion gene, o le TEL-AML1 fusion gene o le auala sili lea e faʻamasino ai le faʻamaʻi o tamaiti e maua i le lymphoblastic leukemia.
Auala
| FAM | TEL-AML1 fusion gene |
| ROX | Pulea i totonu |
Vaega Fa'atekinisi
| Teuina | ≤-18℃ |
| Fa'asa-ola | 9 masina |
| Ituaiga Fa'ata'ita'iga | fa'ata'ita'iga o ga'o ponaivi |
| Ct | ≤40 |
| CV | <5.0% |
| LoD | 1000Kopi/mL |
| Fa'apitoa | E leai se felafolafoa'iga i le va o pusa ma isi genes fusuaga pei ole BCR-ABL, E2A-PBX1, MLL-AF4, AML1-ETO, PML-RARa fusion genes. |
| Meafaigaluega Faatatau | Fa'aogaina Biosystems 7500 Fa'atonu PCR Taimi Moni Fa'aogaina Biosystems 7500 Fa'atonuga PCR Taimi Moni Anapogi QuantStudio®5 Faiga PCR Taimi Moni SLAN-96P Faiga PCR Taimi Moni LightCycler®480 Taimi moni PCR faiga LineGene 9600 Plus Faiga Fa'amatalaga PCR Taimi Moni MA-6000 Taimi Moni Fa'ata'amiloga Fa'avevela BioRad CFX96 Taimi Moni PCR System BioRad CFX Opus 96 Taimi moni PCR System |
Galulue Galuega
RNAprep Toto Mama Aofa'i RNA Extraction Kit (DP433).
