Tagata TEL-AML1 Fusion Gene Mutation
Igoa o oloa
HWTS-TM016 Tagata TEL-AML1 Fusion Gene Mutation Detection Kit (Fluorescence PCR)
Epidemiology
Acute lymphoblastic leukemia (ALL) ole ma'i sili ona taatele ile tamaitiiti. I tausaga talu ai nei, ua suia ai le ma'i leukemia (AL) mai le ituaiga MIC (morphology, immunology, cytogenetics) i le MICM type (fa'aopoopoina o su'ega mole mole biology). I le 1994, na iloa ai o le fusuaga o le TEL i le tamaitiiti na mafua mai i le fa'aliliuina ole chromosomal t(12;21)(p13;q22) ile B-lineage acute lymphoblastic leukemia (ALL). Talu mai le mauaina o le AML1 fusion gene, o le TEL-AML1 fusion gene o le auala sili lea e faʻamasino ai le faʻamaʻi o tamaiti e maua i le lymphoblastic leukemia.
Auala
| FAM | TEL-AML1 fusion gene |
| ROX | Pulea i totonu |
Vaega Fa'ainisinia
| Teuina | ≤-18℃ |
| Fa'asa-ola | 9 masina |
| Ituaiga Fa'ata'ita'iga | fa'ata'ita'iga o ga'o ponaivi |
| Ct | ≤40 |
| CV | <5.0% |
| LoD | 1000Kopi/mL |
| Fa'apitoa | E leai se felafolafoa'iga i le va o pusa ma isi genes fusuaga pei ole BCR-ABL, E2A-PBX1, MLL-AF4, AML1-ETO, PML-RARa fusion genes. |
| Meafaigaluega Faatatau | Fa'aogaina Biosystems 7500 Fa'atonu PCR Taimi Moni Fa'aogaina Biosystems 7500 Fa'atonuga PCR Taimi Moni Anapogi QuantStudio®5 Faiga PCR Taimi Moni SLAN-96P Faiga PCR Taimi Moni LightCycler®480 Taimi moni PCR faiga LineGene 9600 Plus Faiga Fa'amatalaga PCR Taimi Moni MA-6000 Taimi Moni Fua Fa'ata'avale vevela BioRad CFX96 Taimi Moni PCR System BioRad CFX Opus 96 Taimi moni PCR System |
Galulue Galuega
RNAprep Toto Mama Aofa'i RNA Extraction Kit (DP433).
