Mycobacterium Tuberculosis Rifampicin Resistance

Fa'amatalaga Puupuu:

O lenei pusa e fetaui lelei mo le suʻesuʻeina lelei o le suiga o le homozygous i le 507-533 amino acid codon region o le rpoB gene e mafua ai le Mycobacterium tuberculosis rifampicin resistance.


Fa'amatalaga Oloa

Faailoga o oloa

Igoa o oloa

HWTS-RT074A-Mycobacterium Tuberculosis Rifampicin Resistance Detection Pusa (Fluorescence PCR)

Epidemiology

O le Rifampicin na fa'aaogaina lautele i togafitiga o gasegase mamapala talu mai le tuai o 1970s, ma e iai sona aafiaga taua.O le filifiliga muamua lava e fa'apu'upu'u le chemotherapy o tagata mama'i mamapala.O le tetee i le Rifampicin e mafua ona o le suiga o le kenera rpoB.E ui lava o loʻo faʻaauau pea ona faʻaalia fualaau fou e tetee atu ai i le mamapala, ma o loʻo faʻaauau pea le faʻaleleia atili o le aoga o tagata mamaʻi mamaʻi, o loʻo i ai pea le le lava o vailaʻau faʻamaʻi, ma o le tulaga o le faʻaogaina o fualaau faʻatauvaʻa e fai si maualuga.E manino lava, o le Mycobacterium tuberculosis i tagata mamaʻi e maua i le mama mama e le mafai ona faʻaumatia atoa i se taimi talafeagai, lea e iu ai ina oʻo atu i tikeri eseese o vailaʻau faʻasaina i le tino o le tagata maʻi, faʻaumiina le ala o le faʻamaʻi, ma faʻateleina ai le lamatiaga o le oti o le tagata maʻi.O lenei pusa e fetaui lelei mo suʻesuʻega fesoasoani o le Mycobacterium tuberculosis faʻamaʻi ma le suʻesuʻeina o le rifampicin resistance gene, lea e fesoasoani e malamalama ai i le teteʻe o vailaʻau o le mycobacterium tuberculosis e aʻafia e tagata mamaʻi, ma tuʻuina atu auala fesoasoani mo le taʻitaʻiga o vailaʻau.

Epidemiology

 

Igoa Sini Tusitala Quencher
Tali Fa'amauA Tali Fa'amauB Tali Fa'amauC
rpoB 507-514 rpoB 513-520 IS6110 FAM Leai
rpoB 520-527 rpoB 527-533 / CY5 Leai
/ / Pulea totonu HEX(VIC) Leai

 

Vaega Fa'atekinisi

Teuina

≤-18℃ I le pogisa

Fa'asa-ola

9 masina

Ituaiga Fa'ata'ita'iga

Sputum

CV

<5%

LoD

ituaiga vao e tetee i le rifampicin: 2x103siama/mL

mutant homozygous: 2x103siama/mL

Fa'apitoa

E iloa ai le mycobacterium tuberculosis o le vao ma nofoaga o suiga o isi genes tete'e fualaau e pei o katG 315G>C\A, InhA-15C>T, o fa'ai'uga o su'ega e leai se tete'e i le rifampicin, o lona uiga e leai se fa'alavelave fa'asagatau.

Meafaigaluega talafeagai:

SLAN-96P Faiga PCR Taimi Moni(Hongshi Medical Technology Co., Ltd. )

Galulue Galuega


  • Muamua:
  • Sosoo ai:

  • Tusi lau savali iinei ma lafo mai ia i matou