Mycobacterium Tuberculosis Rifampicin Resistance
Igoa o oloa
HWTS-RT074A-Mycobacterium Tuberculosis Rifampicin Resistance Detection Pusa (Fluorescence PCR)
Epidemiology
O le Rifampicin na fa'aaogaina lautele i togafitiga o gasegase mamapala talu mai le tuai o 1970s, ma e iai sona aafiaga taua.O le filifiliga muamua lava e fa'apu'upu'u le chemotherapy o tagata mama'i mamapala.O le tetee i le Rifampicin e mafua ona o le suiga o le kenera rpoB.E ui lava o loʻo faʻaauau pea ona faʻaalia fualaau fou e tetee atu ai i le mamapala, ma o loʻo faʻaauau pea le faʻaleleia atili o le aoga o tagata mamaʻi mamaʻi, o loʻo i ai pea le le lava o vailaʻau faʻamaʻi, ma o le tulaga o le faʻaogaina o fualaau faʻatauvaʻa e fai si maualuga.E manino lava, o le Mycobacterium tuberculosis i tagata mamaʻi e maua i le mama mama e le mafai ona faʻaumatia atoa i se taimi talafeagai, lea e iu ai ina oʻo atu i tikeri eseese o vailaʻau faʻasaina i le tino o le tagata maʻi, faʻaumiina le ala o le faʻamaʻi, ma faʻateleina ai le lamatiaga o le oti o le tagata maʻi.O lenei pusa e fetaui lelei mo suʻesuʻega fesoasoani o le Mycobacterium tuberculosis faʻamaʻi ma le suʻesuʻeina o le rifampicin resistance gene, lea e fesoasoani e malamalama ai i le teteʻe o vailaʻau o le mycobacterium tuberculosis e aʻafia e tagata mamaʻi, ma tuʻuina atu auala fesoasoani mo le taʻitaʻiga o vailaʻau.
Epidemiology
Igoa Sini | Tusitala | Quencher | ||
Tali Fa'amauA | Tali Fa'amauB | Tali Fa'amauC | ||
rpoB 507-514 | rpoB 513-520 | IS6110 | FAM | Leai |
rpoB 520-527 | rpoB 527-533 | / | CY5 | Leai |
/ | / | Pulea totonu | HEX(VIC) | Leai |
Vaega Fa'atekinisi
Teuina | ≤-18℃ I le pogisa |
Fa'asa-ola | 9 masina |
Ituaiga Fa'ata'ita'iga | Sputum |
CV | <5% |
LoD | ituaiga vao e tetee i le rifampicin: 2x103siama/mL mutant homozygous: 2x103siama/mL |
Fa'apitoa | E iloa ai le mycobacterium tuberculosis o le vao ma nofoaga o suiga o isi genes tete'e fualaau e pei o katG 315G>C\A, InhA-15C>T, o fa'ai'uga o su'ega e leai se tete'e i le rifampicin, o lona uiga e leai se fa'alavelave fa'asagatau. |
Meafaigaluega talafeagai: | SLAN-96P Faiga PCR Taimi Moni(Hongshi Medical Technology Co., Ltd. ) |