Faʻatauga o le TB ma DR-TB DIGNOMY RECTRS e #macro & micro -test!

O se auupega fou mo Tuberculisis Diginosis ma Fualaʻau Resicance Resociation: O se augatupulaga fou o loʻo faʻatautaia ai le liberculis o le suʻega

RESIDAS RAMES: CCA: O se ata faʻapitoa e faʻavae i luga o le Tngs ma masini aʻoaʻoga, lea e talafeagai mo tagata e itiiti ifo ma tibrecias

O le ulutala ulutala: tupeta-traping-tragetted i le isi-augatupulaga sequening ma masini toleniga: O le ungatra-togafiti togafiti mo ubular o tubulars o tubular.

Vaitaimi: "Clinica Chimbica Gaxi"

Afai: 6.5

Aso o le Lomiga: Ianuari 2024

Tuʻufaʻatasia ma le Iunivesite o Saina Academy of Sciences ma Beijing Chest Hosper of Invess University, Macro-Suʻega o le The New Steences, o le mea e aʻoaʻoina ai mauaina lagona lelei mo le uberculis i nai siama ma tiberteria ma tubremily menitis, maua ai se fou hypersivity diagnosis metotia mo O le fomaʻi faʻapitoa o le lua ituaiga o le uberculisis, ma fesoasoani i le saʻo pipisi, vailaʻau o vailaʻau o loʻo iloa ai ma togafitiga. I le taimi lava e tasi, ua maua ai o le tagata gasegase Plasma Cfdna e mafai ona faʻaaogaina o se talafeagai faʻataʻitaʻiga ituaiga mo le faʻapopoleina o le tbm.

I lenei suʻesuʻega, 227 plasma ma faʻataʻitaʻiga ma cerebropinal vai faʻapitoa sa faʻaaoga e faʻavae ai le lua o aʻoga faʻapitoa, ma o le fale suʻesuʻe na faʻaaogaina e faʻamaonia ai ata tifaga. O faʻataʻitaʻiga uma sa muamua faʻaaogaina e se faʻapitoa fuafuaina o le puʻeina o le probe pol mo le mycobactactium tuberculos. Ma, faʻavae i luga o le TB-TNGS Conquencess Data, o le faʻataʻitaʻiga faʻataʻitaʻi o loʻo masani ai e faʻatino ai le 5-Fronk Cross-faʻamaoniaina o le Lacesma Races e mauaina. O le mea na mauaina o le mea na maua e aumaia i totonu o le lua suʻega seti o le falemaʻi o loʻo fuafuaina mo le mauaina, ma le suʻega o le tagata aʻoaʻo e iloiloina e le tagata aʻoaʻo. Ma le mea mulimuli, o le faʻailoga faʻataʻitaʻiga o Tubercusis na mauaina.

Ata 1 Schematic ata o suʻesuʻega mamanu

Iuga: E tusa ai ma le faʻapitoa o le CSF Dna faʻataʻitaʻiga (AUC = 0.974) ma plasma cfdna faʻataʻitaʻiga o le 95.65% o le 95.65%, ma O le malamalamaʻaga ma le mea faʻapitoa o Prisma Stric na 82.61% ma le 86.36%. I le auiliiliga o le ata tifaga o le ata o Plasma Cfdna ma Cerebrophinal Slud Dona mai TBM Preyments o le 95.4.45% o le 95.4.45% (42/44). I tamaiti ma le Pumomory Tubercusis, o le Diagostic fuafuaga o lenei suʻesuʻega e sili atu le maaleale i plasma faʻataʻitaʻiga o faʻataʻitaʻiga o le siama i le tagata gasegase.

Ata 2 Iloiloga Faʻatino o Tuberculosis Digignosis faʻataʻitaʻiga mo le faitau aofai o tagata

Ata 3 dignostic iuga o le faapopoleina o faʻataʻitaʻiga

Faaiuga: O se faʻataʻitaʻiga o le faʻataʻitaʻiga o le Diagnostic Product mo Tuberculosis na faʻatuina i lenei suʻesuʻega, e mafai ona maua ai se mea e te maua ai le poto masani o le olicbalry (le lelei aganuu). O le mauaina o le faʻailoga o le faʻailoga o le tiberculosis e faʻavae i luga o plasma Cfdna e ono avea o se talafeagai faʻataʻitaʻiga ituaiga mo le faʻailoaina o le oona (plasmal o le vailaʻau o loʻo faigofie ai o le anrebroplis).

Uluai fesoʻotaʻiga: HTTPS://www.sprentdiredred.com/scathetity/article/pii/PII/S0009898123004990? Via% 3Dihub

Faatomuga puʻupuʻu o Macro & Micro-Schoop Tubercusis Faʻasologa o le iloa oloa

Ile vaʻai atu i le faigata o le faʻataʻitaʻiga o le faʻataʻitaʻiga o tubercusis tagata gasegase ma le tele o manaʻoga, macro & bir-suc-suʻega o loʻo maua ai se faʻasologa o mea 'eseʻese. O le oloa e aofia ai faʻailoga vave o le tuberculisis tagata gasegase, vailaʻau tetee o tiberculis, o le a le le lelei o le o le siama o le siama, ma isi

Faʻasalaina o le Real Daits mo Taberculosis ma MyCabacterlia:

Aitema leai Igoa o oloa Oloa Susuga Mataupu Faʻataʻitaʻiga ituaiga Talosaga talafeagai
Hwts-3012 Faapitoa Tatalaina Suiga Faaaogaina i le auala feololo o faʻataʻitaʻiga o faʻataʻitaʻiga, ua maua ai se numera faʻamaumauga muamua-vasega, suka masini 20230047. fulufulu
Hwts-ngs-p00021 Aotelega o le tomai o le siakiina o le pusa mo le fiafia o le tiberculisive (probe sport metotia) Le-le-osofaʻiga (suavai biopsy) o le le mautonu o le mafaufau mo siama e le masani ai o le siamuni o le pulmary ma le mafaufau; O faʻataʻitaʻiga o tagata masalomia o le aʻafia i le tuberculisis poʻo le le-tibercucis o loʻo suʻesuʻeina pe o le faʻafanua muamua-laina na saunia. O le toto toto, Alveolalar LaVage Finad, Hydrothorax ma Asclaites, Taulaitu Camctage faʻataʻitaʻiga, Cerebropal vai. Lua Tupulaga
Hwts-ngs-t001 Mycobacterailine typpine ma fualaau faasaina o le resictiction disgiget ki (tele le tele o le auala Mycobacterum typping suega, aofia ai ma le MTBC ma 187 NTM;Fualaʻau Resictiction Disction of Mycobacterphium Buberculosis Covers 13 Vailaau ma 16 Core Sgat of the Consictions Force. Sputum, alveolalalar solvage vai, hydrothoraxx ma Asclaites, taulai carcture faʻataʻitaʻiga faʻataʻitaʻiga, cerebropal vai. Lua / Tuapuaga o le Tupulaga Itumalo

Manatu Tāua: HWTS-NGS-T001 Mycobactageium typpines ma fualaau faasaina o le Disction Disctiction (tele-Agmp Amplication Metotia)

Oloa Folasaga

O le oloa e faʻavae i luga o le autu muamua-ma le lua-laina vailaʻau faʻamatalaina i le teve dra deces taiala, mahroroscosidescosides e masani ona faʻaaogaina i nofoaga ext. O ai o le Mycobactertam Tuberculis Roadx Musetion Rutalog, atoa foi ma isi lipotia fualaau faasaina o General Retrications Genes Geness and Stations o tusitusiga ma fuainumera. fale ma fafo.

O le faʻailoaina o le faʻailoaina o loʻo faʻavae i luga o le NTM Systemis o loʻo aoina e le NTM taiala na lomia e le au tusitala Saina o Tuberculois Dirests ma le maliega. O le mamanuina o le taina o Play Prices e mafai ona faʻalauteleina, faʻasologa ma le le lava sili atu nai lo le 190 NTM ituaiga.

E ala i le faʻatatauina o le tele o le tekinolosi o le tekonolosi, o le auvaʻa o meaola ma fualaau faasaina o le mecobactium o le prock pcr, ma le armlicon tuufaatasiga o le taulaiga o le pcer e iloa ai. O oloa faagaeeina e mafai ona fausia i le lona lua-augatupulaga ma le lona tolu-augatupulaga o loʻo faʻatulagaina faletusi, ma tolu-augatupulaga o loʻo mafai ona faʻatinoina le faʻasologa o le promentation. I le faʻatusatusaina ma le iloa o le faʻaaogaina o loʻo iai i totonu o le faʻamaumauga o faʻamaumauga (aofia ai ma le o loʻo fuafuaina i le faʻafanua poʻo le faigofie o fualaau faasaina. Tuufaatasi ma le tagata lava ia-tatalaina sputum faʻataʻitaʻiga togafitiga o Macro & Micro-Suʻega, o le faʻafitauli o le maualalo o le faʻafanua o faʻataʻitaʻiga faʻaaogaina saʻo i le feisaiga slutum faʻataʻitaʻiga.

Oloa maua fua

34fualaau faasaina tetee-uiga o le18anti-tibercusis fualaau faasaina ma6Na iloa fualaau faasaina a NTM, ufiufi297Nofoaga o le tetee atu i ai; Sefulu ituaiga o Mycobacter i Tuberculis ma sili atu nai lo190ituaiga o ntm na iloa.

Lisi 1: Faʻamatalaga o 18 + 6 vailaʻau + 190 + NTM

Oloa lelei

Faʻatupuina le faʻamalosiʻau fetuunaiga: O faʻataʻitaʻiga a le sputm e mafai ona maua saʻo i le faʻatagaina o le tagata e aunoa ma le aganuu.

O le faʻataʻitaʻiga faʻataʻitaʻi e faigofie lava: o le taamilosaga muamua o le faʻatulagaina o faʻagasologa o le faigofie, ma o le fale faufalevai e maeʻa ile 3 itula, lea e faʻalelei atili ai le galuega faʻatino.

O le le mautonu ma le faasagatauina o vailaʻau: Faʻapipiʻi le taina o nofoaga o le MTB ma NTM, o le au tutoʻatasi o loʻo sailia ma fualaau lilo.

Tausaga: Oloa ogatasi, Fetuunai i Mainstam Ilm ma MGI / ITT Platforms.

Oloa faamatalaga

Oloa code Igoa o oloa Mauaina tulaga faamatalaga fautuaina
Hwts-ngs-t001 Mycobacterailine typping ma fualaau faasaina o le resicticy disctication ki (tele le tele o le metotia) Ont, ishumina, mgi, masima pro 16 / 96rxn

Taimi o le taimi: Ian-23-20244