Tagata Cyp2c9 ma Volsoc1 Gree Delemmophism
Igoa o oloa
HWTS-GeP014A-tagata Cyp2c9 ma VKORC1 Gree Pongmmorphism Shot (Freorescence PCR)
Tusi Faamaonia
CO / TFTDA
Leitio
Warfarin o se tuʻutuʻuga faʻamoemoe e masani ona faʻaaogaina i le taimi o le faʻatalanoaga i le taimi nei, lea e sili ona fuafuaina mo le puipuia ma le togafitiga o faʻamaʻi o le nifo. Peitaʻi, o tauataʻuga e faʻatapulaʻaina le litanisi pea ma faʻafetaui lautele i totonu o ituaiga eseese ma tagata taʻitoʻatasi. Fuainumera o loʻo faʻaalia ai o le eseʻesega o le mautu mautu i tagata eseese e mafai ona sili atu nai lo le 20 taimi. O le le mautonu o le toto e tupu i le 15.2% o tagata gasegase aveina Warfarin i tausaga taʻitasi, o le 3.5% atiaʻe le palapala toto. O loʻo faʻaalia e le Pharmacogenicoocomactomacamics o le Genera Dithmorphism o le Placecmorm o le Enzorc1 ma Metaboolin Enzyme Cyp2C9 o le taua o le 'oa o le tele o taua. Warfarin o se mea faʻapitoa o le vitamini k epoxide faʻaititia (vkorc1), ma o loʻo taofia le mea e aofia ai vitamini k ma faʻavavau. O se numera tele o suʻesuʻega ua faʻaalia o le Grey Dothmorism o Vorcmorm o le sili ona taua vaega o loʻo aʻafia ai le tuuga ma tagata eseese i le mea e manaʻomia. Warfarin o metabolized e Cyp2c9, ma lona ogalaau sili ona telegyer o metabolism o taua taua. Tagata taʻitoʻatasi e faʻaaogaina Warfarin e sili atu le maualuga o lamatiaga (faʻalua i le tolu taimi maualuga) o le toto i le amataga o le faʻavae o le faʻaaogaina.
Auala
Oge | Vkorc1 (-1639G> a) |
Cy5 | Cyp2c9 * 3 |
Vic / HEX | IC |
Tulaga faapitoa
Teuina | Suavai: ≤-18 ℃ |
Fata-ola | 12 masina |
Primetien ituaiga | Fou edta anticatoted toto |
CV | ≤5.0% |
Lote | 1.0ng / μl |
Faʻapitoa | E leai se mea na faʻaalu ai ma le isi itu e sili atu ona lelei lava le faʻasologa o le tagata o le tagata faʻamaoni (tagata orp2c19 Grees, tagata RPN2 Gen); faafouga o le cyp2c9 * 13 ma le vkorc1 (37300> a) i fafo atu o le mauaina o le tele o lenei pusa |
Talosaga talafeagai | Faʻaaogaina Biosyystem 7500 Twy-Time PCR polokalama Faʻaaogaina Biossisys 7500 Suʻega Moni-Taimi PCR Aofai o le numera numera-taimi Slan-96p moni-taimi pcr polokalama Malamalama clucklecle®480 moni-taimi pcr system Linegene 9600 Ma le taimi moni-taimi PCR mauaina system system Ma-6000 moni-taimi le aofaiga o le karmlel cymlel Biorad cfx96 moni-taimi pcr system Biorad CFX OPSS 96 moni-taimi pcr system |
Galuega tafe
Fautuaina le faʻaaogaina o le faʻaaogaina: Macro & Micro-Suʻega Vona DNA / RNA-3001-32, HWTS - ROWTS 3006).